tailieunhanh - Triển khai chuyển đổi kháng sinh dự phòng từ đường tiêm sang đường uống trên bệnh nhân sau mổ lấy thai tại Bệnh viện đa khoa Đức Giang

Bài viết "Triển khai chuyển đổi kháng sinh dự phòng từ đường tiêm sang đường uống trên bệnh nhân sau mổ lấy thai tại Bệnh viện đa khoa Đức Giang" được triển khai nhằm phân tích hiệu quả khi chuyển đổi đường dùng kháng sinh dự phòng từ đường tiêm tĩnh mạch sang đường uống trên đối tượng sản phụ sau mổ lấy thai mổ lấy thai. | Nghiên cứu Dược amp Thông tin thuốc 2022 Tập 13 Số 6 trang 18-25 BÀI NGHIÊN CỨU Implementation of Intravenous to Oral Conversion of Antimicrobial Prophylaxis in Caesarean section Experiences from Duc Giang General Hospital Hanoi Vietnam Nguyễn Việt Hưnga Đặng Thị Thanh Huyềnb Nguyễn Thùy Trangc Nguyễn Khắc Thủyc Nguyễn Mai Hoaa Nguyễn Thu Hươngb Hoàng Thái Hòab Nguyễn Hoàng Anha a Vietnam National DI amp ADR Center Hanoi University of Pharmacy b Department of Pharmacy Duc Giang General Hospital c Department of Obstetrics Duc Giang General Hospital Corresponding author 0986520658 anh90tkvn@ ABSTRACT Background Converting from Intravenous to Oral IV-to-PO antibiotics can result in several signi cant bene ts such as decreased length of stay reduced nursing preparation and administration time and improved patient comfort. However a limited number of studies focused on the bene ts of IV-to-PO conversion of antimicrobial prophylaxis. Aim This study aimed at evaluating the e ectiveness of IV-to-PO conversion of prophylactic antibiotics in Caesarean section C-section at the Department of Obstetrics Duc Giang General Hospital. Method This was a prospective interventional study using a retrospective control group. The intervention group included patients undergoing C-section between April 6th 2021 and September 30th 2021 using cefuroxime cefuroxime IV used 60 minutes before surgical incision following 2 oral doses q12h over 24 hours the control group included patient undergoing C-section between January 1st 2020 and December 31st 2020 using routine prophylactic antibiotics. The two groups were matched by the propensity-matching score method. Results 304 patients were enrolled in the study including 152 patients in the intervention group and 152 patients in the control group. There was no di erence in the incidence of surgical site infections between the two groups no case in all groups . The antibiotic cost per surgery of the intervention group was 2 times .