tailieunhanh - Diastolic Heart Failure – part 9

Ảnh hưởng của clorua alagebrium (ALT-711), một máy cắt đường liên kết qua cuốn tiểu thuyết, trong điều trị bệnh nhân cao tuổi bị suy tim tâm trương. J thẻ Fail năm 2005; 11; 191 - 195. 95. Rutter MK, Parise H, Benjamin EJ, Levy D, Larson MG, Meigs JB, et al. Tác động của không dung nạp glucose và kháng insulin trên cấu trúc tim | 284 94. Little WC Zile MR Kitzman DW Hundley WG O Brien TX Degroof RC. The effect of alagebrium chloride ALT-711 a novel glucose cross-link breaker in the treatment of elderly patients with diastolic heart failure. J Card Fail 2005 11 191-195. 95. Rutter MK Parise H Benjamin EJ Levy D Larson MG Meigs JB et al. Impact of glucose intolerance and insulin resistance on cardiac structure and . Marwick function sex-related differences in the Framingham Heart Study. Circulation 2003 107 448-454. 96. Wong CY O Moore-Sullivan T Leano R Byrne N Beller E Marwick TH. Alterations of left ventricular myocardial characteristics associated with obesity. Circulation 2004 110 3081-3087. 97. Marwick TH Wong CY. Role of exercise and metabolism in heart failure with normal ejection fraction. Prog Cardiovasc Dis 2007 49 263-274. 20 Hypertrophic Cardiomyopathy Saidi A. Mohiddin and William J. McKenna Introduction Abnormalities of ventricular and atrial function that result in suboptimal left ventricular LV filling in diastole are thought to be important causes of symptoms and functional limitation in patients with hypertrophic cardiomyopathy HCM . Indeed many of the pathophysiologic mechanisms believed to account for diastolic heart failure are floridly expressed in HCM and HCM may prove a useful supermodel for the study of diastolic heart disease and its treatment. Hypertrophic cardiomyopathy is a genetically determined condition defined by apparently unexplained LV hypertrophy associated with symptoms of myocardial ischemia and heart failure and with increased risk of arrhythmic sudden 2 Clinical practice is largely based on an understanding of disease process in an almost complete absence of randomized trial data dynamic outflow obstruction is often managed invasively defibrillators are used when sudden death risk is deemed relatively high and symptoms of heart failure are treated with negative inotropes and diuretics. While many of these strategies are based on an .