tailieunhanh - Cross-Fourier analysis for differentiating prolonged and self-terminating ventricular tachycardia in isolated rat hearts

In this paper, ventricular tachycardia was performed in Langendorff isolated rat hearts to determine how to discriminate between self-terminating ventricular tachycardia (STVT) and prolonged/sustained ventricular tachycardia (prolonged-VT). | Research Cross-Fourier analysis for differentiating prolonged and self-terminating ventricular tachycardia in isolated rat hearts Le Duy Manh1 2 3 Bui Phuong Thuy2 3 Bui Van Hai4 Man Minh Tan2 3 Trinh Xuan Hoang5 1 Graduate University of Science and Technology Vietnam Academy of Science and Technology 2 Institute of Theoretical and Applied Research Duy Tan University 3 Faculty of Natural Sciences Duy Tan University 4 Le Quy Don Technical University 5 Institute of Physics Vietnam Academy of Science and Technology. Corresponding authors leduymanh@ Received 15 Jan. 2023 Revised 13 Mar. 2023 Accepted 10 May 2023 Published 25 May 2023. DOI https ABSTRACT The interaction between the ventricles and atria in the heart is an important aspect of cardiac function. During ventricular arrhythmias such as ventricular tachycardia and ventricular fibrillation the atrial interbeat interval appears different from that of normal sinus rhythm even though there is no direct electrical connection between the ventricles and atria. To understand this phenomenon bivariate time-series Fourier analysis was performed on ventricular and atrial signals. The results showed different levels of correlation from the ventricles to the atria during ventricular arrhythmias. We found that low interaction was associated with self-terminating ventricular arrhythmias while strong connections were mostly seen in sustained ventricular arrhythmias. These findings suggest that the underlying mechanism behind this interaction may be due to the presence of mechano-electrical coupling which serves as a bridge from the ventricles to the atria reciprocal connections . Keywords Ventricular tachycardia Arrhythmia Bivariate time-series Mechano-electrical coupling. 1. INTRODUCTION Arrhythmia is a severe health issue nowadays. The ventricles the body s primary blood-pumping unit might malfunction causing heart failure. The illness kills most people with .