tailieunhanh - Kikuchi’ s Disease in Children: Clinical Manifestations and Imaging Features

Peripheral cyanosis is common in children at any age and is not important. Central cyanosis is always important but may be missed in a child with severe anaemia or children with pigmented skin. It is detected by looking at the colour of the tongue – blue colouration suggests a saturation of less than 85%. Central cyanosis is not improved by breathing 100% oxygen and its presence should be confirmed by a pulse oximeter. Long standing cyanosis may be associated with ‘clubbing’ of the nails of the hands and feet. Children who have long standing cyanosis develop compensatory polycythaemia and possibly. | J Korean Med Sci 2009 24 1105-9 ISSN 1011-8934 DOI Copyright The Korean Academy of Medical Sciences Kikuchi s Disease in Children Clinical Manifestations and Imaging Features Previously published studies on Kikuchi disease KD have frequently addressed the computed tomography CT findings in the adult population however only a few studies have been reported for the pediatric age group. The purpose of this study is to analyze the clinical characteristics and imaging features of KD in children. Fifteen children 2-14 yr who had a neck CT and pathology diagnosis of KD were included in this study. Clinical features including the duration of lymphadenopathy and fever prognosis and laboratory values were evaluated. We analyzed the sites size and lymph node pattern as seen on their CT scans. The median duration of fever was 10 days. Fourteen patients experienced improvement in their condition although four of these patients experienced recurrent episodes of KD. All patients had affected cervical nodes at level V. Perinodal infiltrates were observed in the affected cervical nodes in 14 cases 93 and non-enhancing necrosis was also noted within the affected cervical nodes in 10 cases 63 . In conclusion the combination of imaging findings in conjunction with clinical findings of KD may help to determine whether or not to perform pathology analysis and follow-up studies. Key Words Lymphatic Diseases Histiocytic Necrotizing Lymphadenitis Child Hye Jeong Han1 Gye-Yeon Lim1 DOng-Myung Yeo1 and Nak-Gyun Chung2 Departments of Radiology and Pediatrics2 St. Mary s Hospital The Catholic University of Korea College of Medicine Seoul Korea Received 9 August 2008 Accepted 23 February 2009 Address for correspondence Gye-Yeon Lim . Department of Radiology St. Mary s Hospital The Catholic University of Korea 62 Yeouido-dong Yeongdeungpo-gu Seoul 50-7 3 Korea Tel Fax E-mail shlgy@ INTRODUCTION Kikuchi disease KD or .