tailieunhanh - Constant or fluctuating hyperglycemias increases cytomembrane stiffness of human umbilical vein endothelial cells in culture: Roles of cytoskeletal rearrangement and nitric oxide synthesis

Previous studies have implicated continuous or intermittent hyperglycemia in altered endotheliumderived nitric oxide (NO) synthesis. NO can regulate both the F-actin cytoskeleton and endothelial cell membrane stiffness. Atomic force microscopy (AFM) is a powerful tool that can be used to study plasma membrane deformability at the single cell level. |

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