tailieunhanh - Ảnh hưởng của sự tái thông lòng mạch sớm tới tiến triển và tiên lượng nhồi máu não cấp

Bài viết trình bày việc tìm hiểu mối liên quan giữa tái thông sớm lòng động mạch tắc với tiến triển và tiên lượng nhồi máu não cấp. Tái thông lòng mạch sớm làm giảm tiến triển vùng nhồi máu và có kết cục lâm sàng sau 3 tháng tốt hơn nhóm không được tái thông. | ẢNH HƯỞNG CỦA SỰ TÁI THÔNG LÒNG NGHIÊN CỨU KHOA HỌC MẠCH SỚM TỚI TIẾN TRIỂN VÀ Scientific research TIÊN LƯỢNG NHỒI MÁU NÃO CẤP The impact of early recanalization on the growth and the prognosis of brain acute ischemic stroke Nguyễn Duy Trinh Phạm Minh Thông Lê Văn Thính summary Purpose to study the impact of early recanalization on the growth and the outcomes of the brain acute ischemia. Method Cerebral MRI was performed in 53 stroke ischemia patients from 1 2010 to 6 2013 with our stroke protocols T2 FLAIR Diffusion perfusion and MR angiography before 6h from onset using Siemens system. We ruled out the patients who had no arterial occlusion on TOF sequence. These patients were treated at Bach mai Hospital with IV thrombolysis IA thrombectomy solitaire stent or without specific treatment. A second MRI was performed at 24h after onset. The patients were divided in to 2 groups recanalization and non-recanalization. We compared the mean infarcted volume before and after treatment of the 2 groups and between the initial and the second MRI of the each group. We compared also the rate of hemorrhage transformation and the clinical outcomes modified Rankin Scale at 3 months of the two groups to assess the impact of early racanalization on ischemic stroke Results 53 patients 31 recanilized 22 non- racanilized . No difference about the age time from onset NIHSS initial volume infracted between 2 groups. The final volume of infaction was 54cm3 versus 141cm3 for the recanalized and non- recanalized patients p . An increased volume of the infarction for non- recanalized patient group 54 versus 141cm3 with significant difference p . There was no difference of symptomatic hemorrhage rate 9 versus p between the non- recanalized and recanalized group. Good clinical outcomes mRs 2 was versus 22 for the recanalized and non- recanalazed group p . Among the patient without recanalization there were 4 patients died 18 and 3 patients with mRs 5 .