tailieunhanh - Dự đoán nguy cơ di căn vào phổi ở bệnh nhân ung thư vú dựa vào biểu hiện của CFAP410

Nghiên cứu chỉ ra CFPAP410 có thể được sử dụng như một chỉ thị độc lập giúp hỗ trợ nhận biết ung thư vú di căn phổi sớm, để từ đó có phương pháp điều trị hiệu quả giúp những bệnh nhân ung thư vú di căn phổi có thể kéo dài thời gian sống. | TNU Journal of Science and Technology 228 13 148 - 156 PREDICTING LUNG METASTASIS POTENTIAL OF BREAST CANCER BASED ON CFAP410 EXPRESSION Hoang Dang Hieu1 Nguyen Thanh Dat2 Nguyen Thi Quynh Mai2 Nguyen Minh Nam2 1Institute of Biotechnology - Vietnam Academy of Sciences 2School of Medicine -Vietnam National University Ho Chi Minh City ARTICLE INFO ABSTRACT Received 12 4 2023 Breast cancer is the most common cancer in women but the main cause of death in breast cancer is metastasis to other organs in the body. Among Revised 04 8 2023 these the lung is one of the common sites of breast cancer metastasis. Published 04 8 2023 Determining whether breast cancer has metastasized or not will make the treatment of patients easier. Therefore the development of a marker to KEYWORDS predict breast cancer metastasis has the potential to facilitate more effective treatment and increase the survival time of breast cancer patients. In this CFAP410 study we analyzed the correlation of Cilia and flagella-associated protein Lung metastasis breast cancer 410 CFAP410 with breast cancer lung metastasis. The results showed Marker that the expression levels of CFAP410 in breast cancer patients without lung metastasis were significantly higher than the expression levels of this Predict gene in patients with lung metastatic breast cancer. In addition patients Survival time with high expression of CFAP410 had a low risk of metastasis and their survival time was also markedly higher than that of patients with low expression levels of CFAP410. Our research also shows that CFAP410 can be used as an independent marker to identify breast cancer lung metastasis early which helps patients receive better treatment and increases survival time for breast cancer lung metastasis patients. DỰ ĐOÁN NGUY CƠ DI CĂN VÀO PHỔI Ở BỆNH NHÂN UNG THƯ VÚ DỰA VÀO BIỂU HIỆN CỦA CFAP410 Hoàng Đăng Hiếu1 Nguyễn Thành Đạt2 Nguyễn Thị Quỳnh Mai2 Nguyễn Minh Nam2 1Viện Công nghệ Sinh học - Viện Hàn lâm và khoa học Việt Nam