tailieunhanh - LaminA/C regulates epigenetic and chromatin architecture changes upon aging of hematopoietic stem cells

The decline of hematopoietic stem cell (HSC) function upon aging contributes to aging-associated immune remodeling and leukemia pathogenesis. Aged HSCs show changes to their epigenome, such as alterations in DNA methylation and histone methylation and acetylation landscapes. |

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