tailieunhanh - Population pharmacokineticpharmacodynamic model of propofol in adolescents undergoing scoliosis surgery with intraoperative wake-up test: A study using Bispectral index and composite auditory evoked potentials as pharmacodynamic endpoints

: In adolescents limited data are available on the pharmacokinetics (PK) and pharmacodynamics (PD) of propofol. In this study we derived a PK-PD model for propofol in adolescents undergoing idiopathic scoliosis surgery with an intraoperative wake-up test with reinduction of anesthesia using both Bispectral Index (BIS) and composite A-line ARX index (cAAI) as endpoints. |

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