tailieunhanh - Acute murine antigen-induced arthritis is not affected by disruption of osteoblastic glucocorticoid signalling

The role of endogenous glucocorticoids (GC) in the initiation and maintenance of rheumatoid arthritis (RA) remains unclear. We demonstrated previously that disruption of GC signalling in osteoblasts results in a profound attenuation of K/BxN serum-induced arthritis, a mouse model of RA. |