tailieunhanh - ROR2 is epigenetically inactivated in the early stages of colorectal neoplasia and is associated with proliferation and migration

Colorectal cancer (CRC) is closely linked to Wnt signalling, with 94 % of cases exhibiting a Wnt related mutation. ROR2 is a receptor tyrosine kinase that is thought to repress β-catenin dependent Wnt signalling. |

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