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Health and Quality of Life Outcomes BioMed Central Commentary Open Access Commentary on using the

Health and Quality of Life Outcomes BioMed Central Commentary Open Access Commentary on using the SF-36 or MOS-HIV in studies of persons with HIV disease Jim Shahriar1, Thomas Delate2, Ron D Hays3 and Stephen Joel Coons*4 Address: 1Quality Programs, Health Care Services, Blue Shield of California, San Francisco, CA 94105, USA, 2Express Scripts, Inc., Office of Research and Planning, Maryland Heights, MO 63043, USA, 3Division of General Internal Medicine and Health Services Research, University of California at Los Angeles, Los Angeles, CA 90095-1736, USA and 4Division of HIV Policy and Outcomes Research, College of Pharmacy, University of Arizona, Tucson, AZ 85721-0207, USA Email: Jim Shahriar -. | BioMed Central Health and Quality of Life Outcomes Commentary Open Access Commentary on using the SF-36 or MOS-HIV in studies of persons with HIV disease Jim Shahriar1 Thomas Delate2 Ron D Hays3 and Stephen Joel Coons 4 Address 1Quality Programs Health Care Services Blue Shield of California San Francisco CA 94105 USA 2Express Scripts Inc. Office of Research and Planning Maryland Heights MO 63043 USA 3Division of General Internal Medicine and Health Services Research University of California at Los Angeles Los Angeles CA 90095-1736 USA and 4Division of HIV Policy and Outcomes Research College of Pharmacy University of Arizona Tucson AZ 85721-0207 USA Email Jim Shahriar - jimsheed@aol.com Thomas Delate - tdelate@express-scripts.com Ron D Hays - hays@rand.org Stephen Joel Coons - coons@pharmacy.arizona.edu Corresponding author Published 09 July 2003 Received 23 June 2003 Accepted 09 July 2003 Health and Quality of Life Outcomes 2003 1 25 This article is available from http www.hqlo.cOm content 1 1 25 2003 Shahriar et al licensee BioMed Central Ltd. This is an Open Access article verbatim copying and redistribution of this article are permitted in all media for any purpose provided this notice is preserved along with the article s original URL. Abstract The purpose was to compare and comment on use of the SF-36 and MOS-HIV instruments in studies of persons with HIV disease. Three medical information databases were searched to identify examples of HIV studies that included the MOS-HIV or SF-36. Thirty-nine and 14 published articles were identified for illustration in comparing the use of the MOS-HIV and SF-36 in HIV disease respectively. Support for the reliability and construct validity of the MOS-HIV and SF-36 was found. Ceiling and floor effects were reported for both the MOS-HIV and SF-36 however ceiling effects were more common for the MOS-HIV in part due to fewer items in the physical social and role functioning domains. The MOS-HIV measures three domains .