tailieunhanh - Health and Quality of Life Outcomes BioMed Central Review Open Access Acromegaly Quality of Life

Health and Quality of Life Outcomes BioMed Central Review Open Access Acromegaly Quality of Life Questionnaire (AcroQoL) Xavier Badia*1, Susan M Webb2, Luis Prieto3 and Nuria Lara1 Address: 1Health Outcomes Research Europe Group, Health Outcomes Research Europe C/Plató 6, 1o, 5a, 08021 Barcelona, Spain, 2Endocrinology Department, Hospital de la Santa Creu i Sant Pau, Sant Antoni MaClaret, 167, 08025 Barcelona, Spain and 3Health Outcomes Research Unit, Lilly SA, Av de la Industria, 30 E-28108 Alcobendas, Madrid, Spain Email: Xavier Badia* - xbadia@; Susan M Webb - swebb@; Luis Prieto - PRIETO_LUIS@; Nuria Lara - nlara@ * Corresponding author Published: 27 February 2004 Health and Quality of Life. | BioMed Central Health and Quality of Life Outcomes Review Acromegaly Quality of Life Questionnaire AcroQoL Xavier Badia 1 Susan M Webb2 Luis Prieto3 and Nuria Lara1 Open Access Address 1Health Outcomes Research Europe Group Health Outcomes Research Europe C Plató 6 1o 5a 08021 Barcelona Spain 2Endocrinology Department Hospital de la Santa Creu i Sant Pau Sant Antoni MaClaret 167 08025 Barcelona Spain and 3Health Outcomes Research Unit Lilly SA Av de la Industria 30 E-28108 Alcobendas Madrid Spain Email Xavier Badia - xbadia@ Susan M Webb - swebb@ Luis Prieto - PRIETO_LUIS@ Nuria Lara - nlara@ Corresponding author Published 27 February 2004 Received 09 January 2004 Accepted 27 February 2004 Health and Quality of Life Outcomes 2004 2 13 This article is available from http content 2 1 1 3 2004 Badia et al licensee BioMed Central Ltd. This is an Open Access article verbatim copying and redistribution of this article are permitted in all media for any purpose provided this notice is preserved along with the article s original URL. Abstract Acromegaly is a chronic disease with an important impact on patients Health Related Quality of Life HRQoL . The ability to effectively measure Health Related Quality of Life is central to describing the impacts of disease or treatment upon the patient therefore the importance of having a disease specific questionnaire for acromegaly. For the development of the AcroQoL questionnaire different sources of information were used first a literature search was performed to identify relevant papers describing the impact of acromegaly in HRQoL second the main domains of impact on HRQoL were identified by 10 experts endocrinologists and third ten indepth semi-structured interviews were conducted in acromegalic patients to identify domains and items related to the self-perceived impact of acromegaly in patients life. After a proper qualitative analysis a preliminary 38 item .

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