tailieunhanh - Hiệu quả nâng huyết áp của phenylephrin trong gây tê tủy sống mổ lấy thai

Bài viết trình bày đánh giá hiệu quả nâng huyết áp của phenylephrin trong gây tê tủy sống mổ lấy thai với mục tiêu so sánh tác dụng nâng huyết áp của phenylephrin với ephedrin trên huyết động trong khi gây tê tủy sổng để mổ lấy thai. | Vietnam Journal of Community Medicine Vol. 64 Special Issue 11 323-327 LOOD PRESSURE INCREASING EFFECT OF PHENYLEPHRIN IN SPINAL ANNESTHESIA FOR C-SECTION Bui Ngoc Duc Huynh Thi Doan Dung Bui Duc Cuong Tay Nguyen Regional General Hospital - 184 Tran Quy Cap Tu An Ward Buon Ma Thuot City Dak Lak Province Vietnam Received 14 09 2023 Revised 07 10 2023 Accepted 02 11 2023 ABSTRACT Background The most common method of anesthesia in cesarean section is spinal anesthesia. This is an effective method avoiding anesthesia complications in pregnant women and newborns easy to perform high success rate anesthetic and good muscle relaxation during surgery. Research on the blood pressure raising effect of phenylephrine during spinal anesthesia with the goal of stabilizing hemodynamics during cesarean section compared to ephedrine. Patients and Methods Clinical trial study randomized controlled comparing the blood pressure raising effects of phenylephrine with ephedrine on hemodynamics during spinal anesthesia for cesarean section in 297 women with indications for cesarean section. Group P phenylephrine 151 pregnant women immediately after birth continuously infused phenylephrine through a separate peripheral intravenous catheter dose of 15 mcg minute until skin closure. Group E ephedrine 146 pregnant women immediately after surgery continuously infused ephedrine through a separate peripheral intravenous catheter dose of mg minute until skin closure. Results Intraoperative blood pressure levels of the phenylephrine and ephedrine infusion groups were equally stable. The average heart rate of the phenylephrine group was at 10 minutes onwards stable and did not increase compared to the ephdrine group which was during surgery . Newborns of both groups had good Apgar scores from the first minute to the 5th minute. Conclusions The blood pressure raising effect of phenylephrine is stable and does not increase heart rate compared to using ephedrine. .

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