tailieunhanh - Nghiên cứu đặc điểm viêm phổi cộng đồng do Enterobacteriaceae sinh ESBL tại Bệnh viện Thống Nhất

Enterobacteriaceae sinh men betalactam phổ rộng (ESBL Enterobacteriaceae) đang trở thành một tác nhân kháng thuốc cao trong viêm phổi cộng đồng. Bài viết trình bày xác định các đặc điểm lâm sàng, cận lâm sàng, các yếu tố nguy cơ, và tiên lượng tử vong của viêm phổi cộng đồng do vi khuẩn Enterobacteriaceae sinh ESBL. | Vietnam Journal of Community Medicine Vol. 64 Special Issue 8 2023 401-411 INSTITUTE OF COMMUNITY HEALTH CHARACTERISTIC OF COMMUNITY ACQUIRED PNEUMONIA CAUSED BY ESBL PRODUCING ENTEROBACTERIACEAE AT THONG NHAT HOSPITAL Le Bao Huy1 2 Vu Dinh Chanh2 Vu Thi Kim Cuong2 Nguyen Thanh Liem2 1 School of Medicine Vietnam National University HoChiMinh City - Dong Hoa ward Di An city Binh Duong Vietnam 2 Thong Nhat Hopital - No. 1 Ly Thuong Kiet Ward 7 Tan Binh District Ho Chi Minh City Vietnam Received 10 07 2023 Revised 28 08 2023 Accepted 25 09 2023 ABSTRACT Background ESBL producing Enterobacteriaceae has become a prominant agent with high antibiotic resistance in community acquired pneumonia CAP . Objectives To aim at finding out the clinical and paraclinical characteristics risk factors and mortality prognosis of CAP caused by ESBL-producing Enterobacteriaceae Subject and method A cross-sectional descriptive study enrolled 118 CAP patients caused by Enterobacteriaceae hospitalized at Thong Nhat hospital from January 2020 to January 2022. They were divided into two groups based on producing ESBL and non ESBL. Results CAP was caused by ESBL-producing Enterobacteriaceae has an average age of years male accounts for . Underlying diseases include cirrhosis alcoholism recent hospitalization within 30 days and use of corticosteroids is more than in the non-ESBL group. Prominent clinical symptoms are consolidation syndrome lobar pneumonia . ESBL-producing agents are with 32 . Enterobacteriaceae MDR accounts for XDR PDR . ESBL-producing Enterobacteriaceae resistant to piperacillin sulbactam 25 ertapenem imipenem still 100 sensitive to meropenem amikacin and colistin. In multivariable regression analysis factors predicting mortality included inappropriate antibiotic use OR 95 CI p ventilation support OR 95 CI - p ICU admission OR 95 CI - .