tailieunhanh - Emergence of anthelmintic resistance in Haemonchus contortus on organized sheep and goat farms of Sub-Himalayan region of Northern India

The present study was planned to know the status of anthelmintic resistance in gastrointestinal (GI) nematodes of two organized sheep and one goat farms of subHimalayan region of northern India using faecal egg count reduction test (FECRT). Three anthelmintics, fenbendazole (FBZ), tetramisole HCl (TMS) and ivermectin (IVM) of benzimidazole, imidazothiazole and macrocyclic lactone groups, respectively were tested at each farm. | 2017 6 10 790-796 International Journal of Current Microbiology and Applied Sciences ISSN 2319-7706 Volume 6 Number 10 2017 pp. 790-796 Journal homepage http Original Research Article https Emergence of Anthelmintic Resistance in Haemonchus contortus on Organized Sheep and Goat Farms of Sub-Himalayan Region of Northern India Rajeev Ranjan Kumar . Yadav and Stuti Vatsya College of Veterinary and Animal Sciences . Pant University of Agriculture and Technology Pantnagar-263145 Uttarakhand India Corresponding author ABSTRACT Keywords The present study was planned to know the status of anthelmintic resistance in gastrointestinal GI nematodes of two organized sheep and one goat farms of sub- Anthelmintic Himalayan region of northern India using faecal egg count reduction test FECRT . Three resistance Haemonchus anthelmintics fenbendazole FBZ tetramisole HCl TMS and ivermectin IVM of contortus benzimidazole imidazothiazole and macrocyclic lactone groups respectively were tested Sheep Goats at each farm. Resistance was detected against FBZ and TMS in all selected farms with Fenbendazole FECRT ranging from -170 to 63 and 18 to 91 respectively. However GI nematodes Tetramisole HCl were found susceptible to IVM in all farms with FECRT ranging from 97 to 100. Pre- Ivermectin. treatment coproculture revealed Haemonchus contortus as the predominant GI nematode followed by Oesophagostomum columbianum and Trichostrongylus colubriformis. Besides Article Info this the larvae of Ostertagia spp. were also recorded in sheep of Kedarkatha farm. Post- Accepted coproculture results revealed the presence of 100 percent larvae of H. contortus only in 07 September 2017 animals treated with FBZ and TMS. This is the first report of Haemonchus being resistant Available Online to both FBZ and TMS at organized farms simultaneously from sub-Himalayan region of 10 October 2017 northern India. Introduction In .