Đang chuẩn bị liên kết để tải về tài liệu:
Báo cáo y học: " Changes in microRNA expression profiles in HIV-1-transfected human cells"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: Changes in microRNA expression profiles in HIV-1-transfected human cells | Retrovirology BioMed Central Short report Open Access Changes in microRNA expression profiles in HIV-l-transfected human cells Man Lung Yeung1 Yamina Bennasser1 Timothy G Myers2 Guojian Jiang2 Monsef Benkirane3 and Kuan-Teh Jeang 1 4 Address 1Molecular Virology Section Laboratory of Molecular Microbiology National Institute of Allergy and Infectious Diseases National Institutes of Health Bethesda Maryland 20892-0460 USA 2Microarray Research Facility Research Technologies Branch National Institute of Allergy and Infectious Diseases National Institutes of Health Bethesda Maryland 20892-8005 USA 3Laboratoire de Virologie Moleculaire Institut de Genetique Humaine CNRS UPR1142 Montpellier France and 4Building 4 Room 306 9000 Rockville Pike Bethesda MD 208920460 USA Email Man Lung Yeung - yeungm@niaid.nih.gov Yamina Bennasser - ybennasser@niaid.nih.gov Timothy G Myers - tmyers@niaid.nih.gov Guojian Jiang - GJiang@niaid.nih.gov Monsef Benkirane - Monsef.BenKirane@igh.cnrs.fr Kuan-Teh Jeang - kj7e@nih.gov Corresponding author Published 28 December 2005 Received 14 December 2005 Accepted 28 December 2005 Retrovirology 2005 2 81 doi l0.ll86 l 742-4690-2-81 H This article is available from http www.retrovirology.cOm content 2 1 81 2005 Yeung et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract MicroRNAs miRNAs are small RNAs of 18-25 nucleotides nt in length that play important roles in regulating a variety of biological processes. Recent studies suggest that cellular miRNAs may serve to control the replication of viruses in cells. If such is the case viruses might be expected to evolve the ability to modulate the expression of cellular miRNAs. To ask if expression of HIV-l genes changes the miRNA profiles in human cells we