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Báo cáo khoa học: "Year in review 2006: Critical Care – paediatrics"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Year in review 2006: Critical Care – paediatrics. | Available online http ccforum.eom content 11 4 222 Review Year in review 2006 Critical Care - paediatrics Carolina F Amoretti1 and Robert C Tasker2 Paediatric Intensive Care Unit BOX 7 Addenbrookes Hospital Hills Road Cambridge CB2 2QQ UK 2University of Cambridge School of Clinical Medicine Department of Paediatrics BOX 116 Addenbrookes Hospital Hills Road Cambridge CB2 2QQ UK Corresponding author Carolina F Amoretti carolina.amoretti@addenbrookes.nhs.uk Published 24 August 2007 This article is online at http ccforum.com content 11 4 222 2007 BioMed Central Ltd Critical Care 2007 11 222 doi 10.1186 cc5946 Abstract In 2006 paediatric intensive care-related subjects were discussed in a number of papers published in various journals including Critical Care. Because they focused on the cardiovascular system and its support we summarize them here. In particular these papers highlighted the management of refractory septic shock extracorporeal support outcome markers in sepsis and outcome after cardiac arrest. Introduction In 2006 the paediatric intensive care PIC cardiovascular-related subjects that were discussed in Critical Care included sepsis viral infection extracorporeal circulatory support and outcome after cardiopulmonary arrest. Sepsis Treatment In children death and morbidity from sepsis and septic shock are particular problems 1 . Hypotensive catecholamine-resistant shock is increasingly recognized as a cause of death in the post-resuscitation period. Arginine-vasopressin AVP and terlipressin TP are capable of improving blood pressure but not without adverse effects such as limb gangrene 2-6 . The action of AVP is mediated via two receptors vascular V1 leading to arterial vasoconstriction and renal tubular V2. Landry and colleagues 2 reported the beneficial effect of AVP in critically ill adults with septic shock resistant to inotropic therapy. AVP and TP have now been studied in both adults and children as rescue therapy for catecholamine-resistant shock 2-5