tailieunhanh - Báo cáo y học: " Year in review 2008: Critical Care - sepsis"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Year in review 2008: Critical Care - sepsis. | Available online http content 13 5 224 Review Year in review 2008 Critical Care - sepsis Steven M Opal1 and Steven P LaRosa2 1 Department of Medicine Infectious Disease Division Memorial Hospital of RI The Warren Alpert Medical School of Brown University 111 Brewster Street Pawtucket RI 02860 USA 2Department of Medicine Infectious Disease Division Rhode Island Hospital The Warren Alpert Medical School of Brown University 593 Eddy Street Providence RI 02903 USA Corresponding author Steven M Opal Steven_Opal@ Published 21 October 2009 This article is online at http content 13 5 224 2009 BioMed Central Ltd Critical Care 2009 13 224 doi cc7945 Abstract The present report highlights the most important papers appearing in Critical Care and other major journals about severe sepsis the systemic inflammatory response and multiorgan dysfunction over the past year. A number of these clinical and laboratory studies will have a considerable impact on the sepsis research agenda for years to come. The steroid controversy the debate over tight glycemic control the colloid versus crystalloid issue the value of selective decontamination of the digestive tract the enlarging role of biomarkers the value of genomics and rapid diagnostic techniques have all been prominently featured in recent publications. Basic research into novel predictive assays genetic polymorphisms and new molecular methods to risk-stratify and to determine treatment options for sepsis have occupied much of the Critical Care publications relating to sepsis pathophysiology in 2008. We will attempt to briefly summarize what we consider to be the most significant contributions to the sepsis literature over the last year and their likely ramifications in the future for critical care clinicians clinical investigators and basic researchers alike. Introduction 2008 was a significant year in Critical Care with a number of landmark papers being published in sepsis research in this .

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