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Báo cáo y học: "DNA variation and brain region-specific expression profiles exhibit different relationships between inbred mouse strains: implications for eQTL mapping studies"

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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: DNA variation and brain region-specific expression profiles exhibit different relationships between inbred mouse strains: implications for eQTL mapping studies. | Research Open Access DNA variation and brain region-specific expression profiles exhibit different relationships between inbred mouse strains implications for eQTL mapping studies liris HovattaH n Matthew A ZapalaH Ron S Broide Eric E Schadt Ondrej Libiger Nicholas J Schork David J Lockhart and Carrolee Barlow n Addresses The Salk Institute for Biological Studies Laboratory of Genetics 10010 North Torrey Pines Road La Jolla CA 92037 USA. National Public Health Institute Department of Molecular Medicine Haartmaninkatu 8 00290 Helsinki Finland. INSERM U513 Neurobiology and Psychiatry Faculte de Médecine 8 rue du General Sarrail Créteil 94010 cedex France. Biomedical Sciences Graduate Program School of Medicine University of California San Diego 9500 Gilman Drive La Jolla CA 92093 USA. Polymorphism Research Laboratory Department of Psychiatry University of California San Diego 9500 Gilman Drive La Jolla CA 92093 USA. Neurome Inc. 11149 North Torrey Pines Road La Jolla CA 92037 USA. Rosetta Inpharmatics Inc. 401 Terry Avenue North Seattle WA 98109 USA. Amicus Therapeutics 6 Ceder Brook Drive Cranbury NJ 08512 USA. ftBrainCells Inc. 10835 Road to the Cure San Diego CA 92121 USA. H These authors contributed equally to this work. Correspondence Carrolee Barlow. Email cbarlow@braincellsinc.com Published 26 February 2007 Genome Biology 2007 8 R25 doi 10.1 186 gb-2007-8-2-r25 The electronic version of this article is the complete one and can be found online at http genomebiology.com 2007 8 2 R25 Received 2 May 2006 Revised 25 July 2006 Accepted 26 February 2007 2007 Hovatta et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. t is I Illi Abstract Background Expression quantitative trait locus eQTL mapping is used to find loci that