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Báo cáo y học: " Spontaneous acute subdural hematoma as an initial presentation of choriocarcinoma: A case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Spontaneous acute subdural hematoma as an initial presentation of choriocarcinoma: A case report | Journal of Medical Case Reports BioMed Central Open Access Case report Spontaneous acute subdural hematoma as an initial presentation of choriocarcinoma A case report Brandon G Rocque and Mustafa K Baskaya Address Department of Neurological Surgery University of Wisconsin Madison WI USA Email Brandon G Rocque - b.rocque@neurosurg.wisc.edu Mustafa K Baẹkaya - m.baskaya@neurosurg.wisc.edu Corresponding authors Published 19 June 2008 Received 30 November 2007 Journal of Medical Case Reports 2008 2 211 doi 10.1186 1752-1947-2-211 Accepted 19 June 2008 This article is available from http www.jmedicalcasereports.cOm content 2 1 21 1 2008 Rocque and Baạkaya licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Diverse sequelae of central nervous system metastasis of choriocarcinoma have been reported including infarction intra or extra axial hemorrhages aneurysm formation and carotid-cavernous fistula. Here we report a case of subdural hematoma as the first presentation of choriocarcinoma. Case presentation The patient is a 34-year-old woman whose initial presentation of widely metastatic choriocarcinoma was an acute subdural hematoma requiring decompressive craniectomy. Histopathologic examination of the tissue showed no evidence of choriocarcinoma but the patient was found to have diffuse metastatic disease and cerebrospinal fluid indices highly suggestive of intracranial metastasis. Conclusion Choriocarcinoma frequently metastasizes intracranially. We review the diverse possible manifestations of this process. In addition the cerebrospinal fluid serum beta-human chorionic gonadotropin ratio is an important factor in diagnosing these cases. Finally the role of the neurosurgeon is discussed. Introduction .