tailieunhanh - Báo cáo y học: "S-100B and neuron-specific enolase as predictors of neurological outcome in patients after cardiac arrest and return of spontaneous circulation: a systematic review"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: S-100B and neuron-specific enolase as predictors of neurological outcome in patients after cardiac arrest and return of spontaneous circulation: a systematic review. | Available online http content 13 4 R121 Research S-100B and neuron-specific enolase as predictors of neurological outcome in patients after cardiac arrest and return of spontaneous circulation a systematic review Koichiro Shinozaki Shigeto Oda Tomohito Sadahiro Masataka Nakamura Yo Hirayama Ryuzo Abe Yoshihisa Tateishi Noriyuki Hattori Tadanaga Shimada and Hiroyuki Hirasawa Department of Emergency and Critical Care Medicine Graduate School of Medicine Chiba University 1 -8-1 Inohana Chuo-ku Chiba City 2608677 Japan Corresponding author Koichiro Shinozaki shino@ Received 14 Apr 2009 Revisions requested 24 May 2009 Revisions received 4 Jun 2009 Accepted 22 Jul 2009 Published 22 Jul 2009 Critical Care 2009 13 R121 doi cc7973 This article is online at http content 13 4 R1 21 2009 Shinozaki et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Neurological prognostic factors after cardiopulmonary resuscitation CPR in patients with cardiac arrest CA as early and accurately as possible are urgently needed to determine therapeutic strategies after successful CPR. In particular serum levels of protein neuron-specific enolase NSE and S-100B are considered promising candidates for neurological predictors and many investigations on the clinical usefulness of these markers have been published. However the design adopted varied from study to study making a systematic literature review extremely difficult. The present review focuses on the following three respects for the study design definitions of outcome value of specificity and time points of blood sampling. Methods A Medline search of literature published before August 2008 was performed using the .

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