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Báo cáo y học: "Effects of plasma expansion with albumin and paracentesis on haemodynamics and kidney function in critically ill cirrhotic patients with tense ascites and hepatorenal syndrome: a prospective uncontrolled trial"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Effects of plasma expansion with albumin and paracentesis on haemodynamics and kidney function in critically ill cirrhotic patients with tense ascites and hepatorenal syndrome: a prospective uncontrolled trial. | Available online http ccforum.eom content 1 2 1 R4 Research Effects of plasma expansion with albumin and paracentesis on haemodynamics and kidney function in critically ill cirrhotic patients with tense ascites and hepatorenal syndrome a prospective uncontrolled trial Andreas Umgelter1 Wolfgang Reindl1 Katrin S Wagner2 Michael Franzen1 Konrad Stock1 Roland M Schmid1 and Wolfgang Huber1 1Medizinische Klinik und Poliklinik der Technischen Universitat Munchen Ismaningerstrasse 22 81675 Munchen Germany 2Klinik fur Kardiologie und Internistische Intensivmedizin Klinikum Bogenhausen Stadtisches Klinikum Munchen GmbH Englschalkinger Strasse 77 81925 Munchen Germany Corresponding author Andreas Umgelter andreas.umgelter@lrz.tu-muenchen.de Received 2 Oct 2007 Revisions requested 24 Nov 2007 Revisions received 27 Nov 2007 Accepted 15 Jan 2008 Published 15 Jan 2008 Critical Care 2008 12 R4 doi 10.1186 cc6765 This article is online at http ccforum.com content 12 1 R4 2008 Umgelter et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Circulatory dysfunction in cirrhotic patients may cause a specific kind of functional renal failure termed hepatorenal syndrome HRS . It contributes to the high incidence of renal failure in cirrhotic intensive care unit ICU patients. Fluid therapy may aggravate renal failure by increasing ascites and intra-abdominal pressure IAP . This study investigates the short-term effects of paracentesis on haemodynamics and kidney function in volume resuscitated patients with HRS. Methods Nineteen consecutive cirrhotic patients with HRS were studied. Circulatory parameters and renal function were analysed before and after plasma expansion and paracentesis. Haemodynamic monitoring .