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Báo cáo y học: "Palatal tremor after lithium and carbamazepine use: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Palatal tremor after lithium and carbamazepine use: a case report. | Mahasuar et al. Journal of Medical Case Reports 2010 4 176 http www.jmedicalcasereports.eom content 4 1 176 jA JOURNALOF.MEDICAL CASE REPORTS CASE REPORT Open Access Palatal tremor after lithium and carbamazepine use a case report Rajnarayan Mahasuar Anju Kuruvilla and KS Jacob Abstract Introduction Palatal tremor characterized by rhythmic contractions of the soft palate can occur secondary to pathology in the dentato-rubro-olivary pathway or in the absence of such structural lesions. Its pathogenesis is only partially understood. We describe a case of probable drug-induced palatal tremor. Case presentation A 27-year-old Indian man had taken carbamazepine and lithium for 7 years for the treatment of a manic episode. He presented with a one-year history of bilateral rhythmic oscillations of his soft palate and tremors of his tongue. There were no other abnormalities detected from his examination or after detailed investigation. Conclusion Palatal tremors may result from medication used in the treatment of psychiatric disorders. Introduction Palatal tremor PT previously referred to as palatal myoclonus is characterized by rhythmic contractions of the soft palate. Symptomatic PT is diagnosed secondary to lesions in the dentato-rubro-olivary pathway. On the other hand essential PT has no known structural lesions. Bipolar affective disorder is a mental illness with an annual incidence of less than 1 and a lifetime prevalence of 0 to 7.8 1 . It is characterized by recurrent periods of depression that alternate with periods of hypomania or mania. Mood stabilizers such as lithium sodium valproate and carbamazepine are recommended in the treatment of acute mania. These are also used as prophylactic agents in the treatment of bipolar disorders 2 . We report the case of a patient with PT associated with the prolonged use of lithium and carbamazepine. Case presentation A 27-year-old Indian man presented with complaints of a clicking sound upon partially opening his mouth. He .