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Báo cáo y học: " Magnetic resonance imaging with pathological correlation in a case of mantle cell lymphoma of the parotid gland: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài:Magnetic resonance imaging with pathological correlation in a case of mantle cell lymphoma of the parotid gland: a case report | Pilavaki et al. Journal of Medical Case Reports 2010 4 99 http www.jmedicalcasereports.eom content 4 1 99 jAc JOURNALOF medical ÌỤr case REPORTS CASE REPORT Open Access Magnetic resonance imaging with pathological correlation in a case of mantle cell lymphoma of the parotid gland a case report 1 23 1 1 Mayia Pilavaki Anastasia Athanasiadou Fotis lordanidis Thrasivulos Karakozoglou Panagiotis Palladas Abstract Introduction Mantle cell lymphoma is a rare non-Hodgkin s lymphoma. It is a subtype of B-cell lymphoma with frequent involvement of the bone marrow and the gastrointestinal tract. Isolated parotid gland involvement seldom occurs. Here we report an unusual case of isolated infiltration of the parotid gland by mantle cell lymphoma. The aim of our study is to correlate magnetic resonance imaging findings with the histological features of the disease. To the best of our knowledge no similar radiological findings of mantle cell lymphoma have been published before. Case presentation A 72-year-old Caucasian woman presented with a painful left parotid enlargement. She was diagnosed with mantle cell lymphoma involving the left submandibular gland seven years prior to presentation. Her whole body CT scan showed the absence of pathologically enlarged lymph nodes. However a magnetic resonance imaging showed enlargement of her left parotid gland and an abnormal parenchyma with mixed-type solid and cystic lesions. A biopsy of her left parotid gland and subsequent histological examination confirmed a mantle cell lymphoma common variant relapse. Conclusion Although rare the involvement of parotid gland with mantle cell lymphoma must be considered in the differential diagnosis of parotid tumors. Introduction Mantle cell lymphoma MCL is a rare lymphoma that accounts for approximately 5 to 7 of non-Hodgkin s lymphomas NHL . It is usually characterized by an aggressive clinical course with a median overall survival of two to five years 1 . The involvement of extranodal sites is .