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Báo cáo y học: "Noninvasive positive pressure ventilation for respiratory failure caused by exacerbations of chronic obstructive pulmonary disease: a standard of care"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về y học đề tài: Noninvasive positive pressure ventilation for respiratory failure caused by exacerbations of chronic obstructive pulmonary disease: a standard of care? | Critical Care December 2003 Vol 7 No 6 Hill Commentary Noninvasive positive pressure ventilation for respiratory failure caused by exacerbations of chronic obstructive pulmonary disease a standard of care Nicholas S Hill Pulmonary Critical Care and Sleep Division TUFTS - New England Medical Center Boston MA USA Correspondence Nicholas S Hill nhill@tufts-nemc.org Published online 30 May 2003 Critical Care 2003 7 400-401 DOI 10.1186 cc2335 This article is online at http ccforum.com content 7 6 400 2003 BioMed Central Ltd Print ISSN 1364-8535 Online ISSN 1466-609X Abstract This editorial comments on a meta-analysis of the use of noninvasive positive pressure ventilation to treat patients with acute respiratory failure caused by chronic obstructive pulmonary disease COPD exacerbations published in the British Medical Journal earlier this year. Based on its analysis of seven randomized controlled trials that met pre-specified criteria the meta-analysis demonstrated highly significant benefits of noninvasive positive pressure ventilation in COPD patients including a reduction in a combined end-point consisting of death and endotracheal intubation. The editorial argues that based on the strength of this and other evidence noninvasive positive pressure ventilation to treat selected patients with acute respiratory failure due to COPD exacerbations should now be considered a standard of care. Keywords acute respiratory failure chronic obstructive pulmonary disease COPD exacerbation mechanical ventilation noninvasive ventilation In a recent issue of the British Medical Journal Lightowler and coworkers 1 presented a meta-analysis of seven randomized controlled trials of noninvasive positive pressure ventilation NPPV to treat acute respiratory failure caused by chronic obstructive pulmonary disease COPD exacerbations as compared with usual care . Their analysis showed substantial and statistically significant reductions in mortality relative risk 0.41 intubation relative risk .