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Báo cáo khoa học: "Steroid hormone receptors ERα and PR characterised by immunohistochemistry in the mare adrenal gland"

Tuyển tập các báo cáo nghiên cứu về bệnh học thý y được đăng trên tạp chí Acta Veterinaria Scandinavica cung cấp cho các bạn kiến thức về bệnh thú y đề tài: Steroid hormone receptors ERα and PR characterised by immunohistochemistry in the mare adrenal gland. | Acta Veterinaria Scandinavica BioMed Central Open Access Steroid hormone receptors ERa and PR characterised by immunohistochemistry in the mare adrenal gland Ylva Hedberg Alm 1 Sayamon Sukjumlong3 Hans Kindahl2 and Anne-Marie Dalin2 Address University Animal Hospital Swedish University of Agricultural Sciences P.O. Box 7040 SE-750 07 Uppsala Sweden 2Division of Reproduction Department of Clinical Sciences Swedish University of Agricultural Sciences P.O. Box 7054 SE-750 07 Uppsala Sweden and 3Department of Anatomy Faculty of Veterinary Science Chulalongkorn University Bangkok Thailand Email Ylva Hedberg Alm - ylva.hedberg.alm@uds.slu.se Sayamon Sukjumlong - Sayamon.S@Chula.ac.th Hans Kindahl - hans.kindahl@kv.slu.se Anne-Marie Dalin - anne-marie.dalin@kv.slu.se Corresponding author Published 22 July 2009 Received 19 October 2008 Acta Veterinaria Scandinavian 2009 51 31 doi 10.1186 1751-0147-51-31 Accepted 22 July 2009 This article is available from http www.actavetscand.cOm content 51 1 31 2009 Alm et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Sex steroid hormone receptors have been identified in the adrenal gland of rat sheep and rhesus monkey indicating a direct effect of sex steroids on adrenal gland function. Methods In the present study immunohistochemistry using two different mouse monoclonal antibodies was employed to determine the presence of oestrogen receptor alpha ERalpha and progesterone receptor PR in the mare adrenal gland. Adrenal glands from intact n 5 and ovariectomised OVX n 5 mares as well as uterine tissue n 9 were collected after euthanasia. Three of the OVX mares were treated with a single intramuscular injection of oestradiol benzoate 2.5 mg 18 - 22 hours prior to euthanasia