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Báo cáo khoa hoc:" Lack of association between mutations of gene-encoding mitochondrial D310 (displacement loop) mononucleotide repeat and oxidative stress in chronic dialysis patients in Taiwan"

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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Lack of association between mutations of gene-encoding mitochondrial D310 (displacement loop) mononucleotide repeat and oxidative stress in chronic dialysis patients in Taiwan | Journal of Negative Results in BioMedicine BioMed Central Research Lack of association between mutations of gene-encoding mitochondrial D310 displacement loop mononucleotide repeat and oxidative stress in chronic dialysis patients in Taiwan Jin-Bor Chen1 Tsu-Kung Lin2 Shang-Chih Liao 1 Wen-Chin Lee1 Lung- Chih Lee1 Chia-Wei Liou2 Pei-Wen Wang3 and Mao-Meng Tiao4 Address 1Nephrology Division Chang Gung Memorial Hospital-Kaohsiung Medical Center Chang Gung University College of Medicine Taiwan 2Department of Neurology Chang Gung Memorial Hospital-Kaohsiung Medical Center Chang Gung University College of Medicine Taiwan 3Endocrine Division Chang Gung Memorial Hospital-Kaohsiung Medical Center Chang Gung University College of Medicine Taiwan and 4Department of Pediatrics Chang Gung Memorial Hospital-Kaohsiung Medical Center Chang Gung University College of Medicine Taiwan Email Jin-Bor Chen - jbchen1@ms5.hinet.net Tsu-Kung Lin - tklin@adm.cgmh.org.tw Shang-Chih Liao - shangchi@adm.cgmh.org.tw WenChin Lee - leewc@adm.cgmh.org.tw Lung-Chih Lee - longee@ms19.url.com.tw Chia-Wei Liou - cwliou@ms22.hinet.net Pei- Wen Wang - wangpw@ms18.hinet.net Mao-Meng Tiao - tmm@cgmh.org.tw Corresponding author Open Access Published 5 November 2009 Received II February 2009 Journal of Negative Results in BioMedicine 2009 8 10 doi 10.1186 1477-5751-8-10 Accepted 5 November 2009 This article is available from http www.jnrbm.com content 8 1 10 2009 Chen et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Mitochondria mt are highly susceptible to reactive oxygen species ROS . In this study we investigated the association between a region within the displacement loop D-loop in mtDNA that is highly susceptible to ROS and oxidative

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