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FUNCTIONAL EVALUATION DISTINGUISHES MCI PATIENTS FROM HEALTHY ELDERLY PEOPLE - THE ADCS/MCI/ADL SCALE

This discussion first reviews early theoretical clarifications of how population health change is linked to reduction in mortality at older ages. We briefly discuss evidence of trends prior to recent decades, subsequent understanding of trends from empirical models of health, and developments in understanding the dimensions of health and the process of health change for an aging population. Recent trends in each dimension of health are then reviewed, ending with a discussion of trends in healthy life, which is a combination of mortality and morbidity dimensions | The Journal of Nutrition Health Aging Volume 14 Number 8 2010 JNHA CLINICAL TRIALS AND AGING FUNCTIONAL EVALUATION DISTINGUISHES MCI PATIENTS FROM HEALTHY ELDERLY PEOPLE - THE ADCS MCI ADL SCALE H. PEDROSA1 A. DE SA2 M. GUERREIRO1 3 J. MAROCO4 M.R. SIMOES5 D. GALASKO6 A. DE MENDONCA17 1. Dementia Clinics Institute of Molecular Medicine and Faculty of Medicine of Lisbon Lisbon Portugal 2. Neurology Clinics Hospital of Santo André Leiria Portugal 3. Laboratory of Language Institute of Molecular Medicine and Faculty of Medicine of Lisbon Lisbon Portugal 4. Superior Institute of Applied Psychology Lisbon Portugal 5. Psychological Assessment Service Faculty of Psychology and Educational Sciences of the University of Coimbra Coimbra Portugal 6. Department of Neurosciences University of California San Diego US 7. Laboratory of Neurosciences Institute of Molecular Medicine and Faculty of Medicine of Lisbon Lisbon Portugal. Corresponding author and reprint requests Alexandre de Mendonẹa Laboratory of Neurosciences Institute of Molecular Medicine Av Prof Egas Moniz 1649-028 Lisbon Portugal Telephone 351217985183 Telefax 351217999454 mendonca@fm.ul.pt Abstract Patients with MCI may present minor impairments in activities of daily living ADL . The main objective of this work was to evaluate the ability of two versions of the Alzheimer s Disease Cooperative Study Activities of Daily Living scale adapted for MCI patients ADCS MCI ADL18 and ADCS McI ADL24 to distinguish patients with MCI from healthy control subjects. Participants were 60 years or older and community dwelling 31 control subjects 30 aMCI patients and 33 AD patients. A protocol of neuropsychological tests global evaluation scales functional scales and depressive symptoms assessment was used. Activities of balancing the cheque book using a telephone going shopping taking medication regularly finding objects talking about current events watching television initiating complex activities keeping appointments or .