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Báo cáo y học: "At-TAX: a whole genome tiling array resource for developmental expression analysis and transcript identification in Arabidopsis thaliana"
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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: At-TAX: a whole genome tiling array resource for developmental expression analysis and transcript identification in Arabidopsis thaliana. | Open Access At-TAX a whole genome tiling array resource for developmental expression analysis and transcript identification in Arabidopsis thaliana Sascha Laubinger Georg Zeller Stefan R Henz Timo Sachsenberg Christian K Widmer Naira Naouar Marnik Vuylsteke Bernhard Scholkopffl Gunnar Ratsch and Detlef Weigel Addresses Department of Molecular Biology Max Planck Institute for Developmental Biology Spemannstr. 37-39 72076 Tubingen Germany. Friedrich Miescher Laboratory of the Max Planck Society Spemannstr. 39 72076 Tubingen Germany. Department of Plant Systems Biology VIB Technologiepark 927 9052 Ghent Belgium. Department of Molecular Genetics Ghent University Technologiepark 927 9052 Ghent Belgium. Department of Empirical Inference Max Planck Institute for Biological Cybernetics Spemannstr. 38 72076 Tubingen Germany. Correspondence Detlef Weigel. Email weigel@weigelworld.org Published 9 July 2008 Genome Biology 2008 9 R112 doi 10.1186 gb-2008-9-7-r1 12 The electronic version of this article is the complete one and can be found online at http genomebiology.com 2008 9 7 R112 Received 15 May 2008 Revised 12 June 2008 Accepted 9 July 2008 2008 Laubinger et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Gene expression maps for model organisms including Arabidopsis thaliana have typically been created using gene-centric expression arrays. Here we describe a comprehensive expression atlas Arabidopsis thaliana Tiling Array Express At-TAX which is based on whole-genome tiling arrays. We demonstrate that tiling arrays are accurate tools for gene expression analysis and identified more than 1 000 unannotated transcribed regions. Visualizations of gene expression estimates transcribed regions and tiling probe measurements