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Báo cáo y học: "ArrayPlex: distributed, interactive and programmatic access to genome sequence, annotation, ontology, and analytical toolsets"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: ArrayPlex: distributed, interactive and programmatic access to genome sequence, annotation, ontology, and analytical toolsets | Open Access Software ArrayPlex distributed interactive and programmatic access to genome sequence annotation ontology and analytical toolsets Patrick J Killion and Vishwanath R Iyer Address Center for Systems and Synthetic Biology Institute for Cellular and Molecular Biology Section of Molecular Genetics and Microbiology University of Texas at Austin 1 University Station A4800 Austin Texas 78712 USA. Correspondence Vishwanath R Iyer. Email vishy@mail.utexas.edu Published 12 November 2008 Genome Biology 2008 9 R159 doi 10.1186 gb-2008-9- 11-r159 The electronic version of this article is the complete one and can be found online at http genomebiology.com 2008 9 11 R159 Received 22 September 2008 Revised 22 September 2008 Accepted 12 November 2008 2008 Killion and Iyer licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract ArrayPlex is a software package that centrally provides a large number of flexible toolsets useful for functional genomics including microarray data storage quality assessments data visualization gene annotation retrieval statistical tests genomic sequence retrieval and motif analysis. It uses a client-server architecture based on open source components provides graphical command-line and programmatic access to all needed resources and is extensible by virtue of a documented application programming interface. ArrayPlex is available at http sourceforge.net projects arrayplex . Rationale Although centralized storage of microarray data is provided by a number of databases such as ArrayExpress Gene Expression Omnibus Stanford Microarray Database Long-horn Array Database Bioarray Software Environment and TM4 1-6 many common downstream analysis procedures remain challenging especially when reference to .