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Báo cáo y học: " xGDB: open-source computational infrastructure for the integrated evaluation and analysis of genome features"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: xGDB: open-source computational infrastructure for the integrated evaluation and analysis of genome features . | Open Access Software xGDB open-source computational infrastructure for the integrated evaluation and analysis of genome features Shannon D Schlueter Matthew D Wilkerson Qunfeng Dong and Volker Brendel Addresses Department of Genetics Development and Cell Biology Iowa State University Ames Iowa 50011-3260 USA. Department of Agronomy Purdue University West Lafayette Indiana 47907 USA. Center for Genomics and Bioinformatics Indiana University Bloomington Indiana 47405-3700 USA. Department of Statistics Iowa State University Ames Iowa 50011-3260 USA. Correspondence Volker Brendel. Email vbrendel@iastate.edu Published 20 November 2006 Genome Biology 2006 7 R111 doi l0.ll86 gb-2006-7-ll-rlll The electronic version of this article is the complete one and can be found online at http genomebiology.com 2006 7 ll Rl ll Received 17 July 2006 Revised 2 August 2006 Accepted 20 November 2006 2006 Schlueter et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract The eXtensible Genome Data Broker xGDB provides a software infrastructure consisting of integrated tools for the storage display and analysis of genome features in their genomic context. Common features include gene structure annotations spliced alignments mapping of repetitive sequence and microarray probes but the software supports inclusion of any property that can be associated with a genomic location. The xGDB distribution and user support utilities are available online at the xGDB project website http xgdb.sourceforge.net . Rationale Computational infrastructure is vital for all aspects of genome research. The assembled genomic sequence of an organism provides a natural scaffold for organizing biologic data. However researchers are easily overwhelmed if they do not .