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Báo cáo y học: "Genome-scale evidence of the nematode-arthropod clade"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Genome-scale evidence of the nematode-arthropod clade. | Research Open Access Genome-scale evidence of the nematode-arthropod clade Hernán Dopazo and Joaquin Dopazo Addresses Pharmacogenomics and Comparative Genomics Unit Bioinformatics Department Centro de Investigation Principe Felipe Autopista del Saler 16 46013 Valencia Spain. Functional Genomics Unit Bioinformatics Department Centro de Investigation Principe Felipe Autopista del Saler 16 46013 Valencia Spain. Functional Genomics Node INB Centro de Investigation Principe Felipe Autopista del Saler 16 46013 Valencia Spain. Correspondence Joaquin Dopazo. E-mail jdopazo@ochoa.fib.es Published 28 April 2005 Genome Biology 2005 6 R41 doi 10.1 186 gb-2005-6-5-r41 The electronic version of this article is the complete one and can be found online at http genomebiology.com 2005 6 5 R41 Received 7 March 2005 Accepted 6 April 2005 2005 Dopazo and Dopazo licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The issue of whether coelomates form a single clade the Coelomata or whether all animals that moult an exoskeleton such as the coelomate arthropods and the pseudocoelomate nematodes form a distinct clade the Ecdysozoa is the most puzzling issue in animal systematics and a major open-ended subject in evolutionary biology. Previous single-gene and genome-scale analyses designed to resolve the issue have produced contradictory results. Here we present the first genome-scale phylogenetic evidence that strongly supports the Ecdysozoa hypothesis. Results Through the most extensive phylogenetic analysis carried out to date the complete genomes of 11 eukaryotic species have been analyzed in order to find homologous sequences derived from 18 human chromosomes. Phylogenetic analysis of datasets showing an increased adjustment to .