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Báo cáo y học: "Year in review 2009: Critical Care – infection"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: Year in review 2009: Critical Care – infection. | Harbarth and Haustein Critical Care 2010 14 240 http ccforum.eom content 14 6 240 CRITICAL CARE REVIEW L_ Year in review 2009 Critical Care - infection Stephan Harbarth and Thomas Haustein Abstract In 2009 Critical Care provided important and clinically relevant research data for management and prevention of infections in critically ill patients. The present review summarises the results of these observational studies and clinical trials and discusses them in the context of the current relevant scientific and clinical background. In particular we discuss recent epidemiologic data on nosocomial infections in intensive care units present new approaches to prevention of ventilator-associated pneumonia describe recent advances in biomarker-guided antibiotic stewardship and attempt to briefly summarise specific challenges related to the management of infections caused by multidrugresistant microorganisms and influenza A H1N1 . Introduction The year 2009 was again an interesting one for readers interested in the field of infection in critically ill patients. Several promising new approaches for the prevention of infections in the intensive care unit ICU setting were presented. Furthermore progress was noted in the difficult area of antimicrobial stewardship and risk stratification of infected patients. Finally several challenges related to influenza infections and the management of difficult-to-treat infections were tackled or better delineated 1 . The present short review will summarise the results of a selection of original studies with a special focus on articles published in Critical Care in 2009. Epidemiology of infection in critically ill patients New insights were reported regarding the epidemiology of infection in ICUs. A global observational study EPIC II on the prevalence and outcomes of infection in 1 265 ICUs was conducted in 75 countries in May 2007. Among the 13 796 patients 9 084 66 patients received an antimicrobial agent and 7 087 51 patients were