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Synthesis and cytotoxicity evaluation of 2-benzoylbenzoxazoles by reaction of o-aminophenol with acetophenone catalyzed by sulfur in DMSO

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The 2-benzoylbenzoxazole derivatives were known for their significant biological activities such as antiproliferative activity, inhibition of FAAH enzyme (fatty acid amide hydrolase). In this study, we report a simple and efficient method for the synthesis of such compounds by the direct reaction of o-aminophenol with acetophenone catalyzed by sulfur in DMSO. |

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