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A nonsense mutation of bone morphogenetic protein-15 (BMP15) causes both infertility and increased litter size in pigs

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Atypical external genitalia are often a sign of reproductive organ pathologies and infertility with both environmental or genetic causes, including karyotypic abnormalities. Genome-wide association studies (GWAS) provide a means for identifying chromosomal regions harboring deleterious DNA-variants causing such phenotypes. |

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Báo cáo y học: "Making sense of nonsense: the evolution of selenocysteine usage in proteins"

Báo cáo sinh học: " Codon usage in vertebrates is associated with a low risk of acquiring nonsense mutations"

Báo cáo y học: "High resolution transcriptome maps for wild-type and nonsense-mediated decay-defective Caenorhabditis elegans."