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Cytotoxicity of purified listeriolysin O on mouse and human leukocytes and leukaemia cells
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Listeriolysin O (LLO) is the main virulence factor of Listeria monocytogenes and facilitates the intracellular survival of the pathogen. Some of its characteristics endorse the growing popularity of LLO for use in biotechnology, particularly in the development of novel vaccines. Here, we evaluate the use of LLO to eradicate leukaemia cells. | Cytotoxicity of purified listeriolysin O on mouse and human leukocytes and leukaemia cells