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Báo cáo y học: "The Autism - Tics, AD/HD and other Comorbidities inventory (A-TAC): further validation of a telephone interview for epidemiological research"

The Autism - Tics, AD/HD and other Comorbidities inventory (A-TAC): further validation of a telephone interview for epidemiological research | Larson et al. BMC Psychiatry 2010 10 1 http www.biomedcentral.eom 1471-244X 10 1 BMC Psychiatry RESEARCH ARTICLE Open Access The Autism - Tics AD HD and other Comorbidities inventory A-TAC further validation of a telephone interview for epidemiological research Tomas Larson1 Henrik Anckarsater1 2 Carina Gillberg2 Ola Stahlberg2 Eva Carlstrom3 Bjorn Kadesjo2 Maria Rastam1 Paul Lichtenstein3 Christopher Gillberg2 Abstract Background Reliable valid and easy-to-administer instruments to identify possible caseness and to provide proxies for clinical diagnoses are needed in epidemiological research on child and adolescent mental health. The aim of this study is to provide further validity data for a parent telephone interview focused on Autism - Tics Attention-deficit hyperactivity disorder AD HD and other Comorbidities A-TAC for which reliability and preliminary validation data have been previously reported. Methods Parents of 91 children clinically diagnosed at a specialized Child Neuropsychiatric Clinic 366 control children and 319 children for whom clinical diagnoses had been previously assigned were interviewed by the A-TAC over the phone. Interviewers were blind to clinical information. Different scores from the A-TAC were compared to the diagnostic outcome. Results Areas under ROC curves for interview scores as predictors of clinical diagnoses were around 0.95 for most disorders including autism spectrum disorders ASDs attention deficit hyperactivity disorder AD HD tic disorders developmental coordination disorders DCD and learning disorders indicating excellent screening properties. Screening cut-off scores with sensitivities above 0.90 0.95 for ASD and AD HD were established for most conditions as well as cut-off scores to identify proxies to clinical diagnoses with specificities above 0.90 0.95 for ASD and AD HD . Conclusions The previously reported validity of the A-TAC was supported by this larger replication study using broader scales from the A-TAC-items .