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Báo cáo y học: " Clinical review: Status epilepticus"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Clinical review: Status epilepticus. | Available online http ccforum.eom content 6 2 137 Review Clinical review Status epilepticus Sarice Bassin Teresa L Smith and Thomas P Bleck Senior Resident in Neurology Department of Neurology University of Virginia Charlottesville Virginia USA Neurology Critical Care Fellow and Clinical Instructor of Neurology Department of Neurology University of Virginia Charlottesville Virginia USA The Louise Nerancy Eminent Scholar in Neurology and Departments of Neurology Neurological Surgery and Internal Medicine Director Neuroscience Intensive Care Unit University of Virginia Charlottesville Virginia USA Correspondence Teresa L Smith tls2u@virignia.edu Published online 15 March 2002 Critical Care 2002 6 137-142 2002 BioMed Central Ltd Print ISSN 1364-8535 Online ISSN 1466-609X Abstract Status epilepticus SE has an annual incidence exceeding 100 000 cases in the United States alone of which more than 20 result in death. Thus increased awareness of presentation etiologies and treatment of SE is essential in the practice of critical care medicine. This review discusses current definitions of SE as well as its clinical presentation and classification. The recent literature on epidemiology is reviewed including morbidity and mortality data. An overview of the systemic pathophysiologic effects of SE is presented. Finally significant studies on the treatment of acute SE and refractory SE are reviewed including the use of anticonvulsants such as benzodiazepines and other drugs. Keywords anticonvulsants benzodiazepine epidemiology review status epilepticus Status epilepticus SE is a medical and neurologic emergency. Given the significant risk of mortality and the possibility of successful therapeutic intervention it is essential for all physicians to be able to efficiently identify and treat patients in SE. Definition The definition of SE is based on the clinical manifestation a prolonged seizure or a series of seizures during which the patient has incomplete recovery of .