tailieunhanh - Báo cáo y học: "Clinical review: A review and analysis of heart rate variability and the diagnosis and prognosis of infection"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Clinical review: A review and analysis of heart rate variability and the diagnosis and prognosis of infection. | Available online http content 13 6 232 Review Clinical review A review and analysis of heart rate variability and the diagnosis and prognosis of infection Saif Ahmad1 Anjali Tejuja1 Kimberley D Newman1 Ryan Zarychanski2 3 and Andrew JE Seely1 4 5 Ottawa Hospital Research Institute Ottawa Ontario K1Y 4E9 Canada 2Section of Critical Care Department of Internal Medicine University of Manitoba Winnipeg Manitoba R3A 1R9 Canada 3Department of Haematology and Medical Oncology CancerCare Manitoba Winnipeg Manitoba R3E 0V9 Canada 4Division of Thoracic Surgery University of Ottawa Ottawa Ontario K1H 8L6 Canada 5Department of Critical Care Medicine University of Ottawa Ottawa Ontario K1H 8L6 Canada Corresponding author Andrew JE Seely aseely@ Published 24 November 2009 This article is online at http content 13 6 232 2009 BioMed Central Ltd Critical Care 2009 13 232 doi cc8132 Abstract Bacterial infection leading to organ failure is the most common cause of death in critically ill patients. Early diagnosis and expeditious treatment is a cornerstone of therapy. Evaluating the systemic host response to infection as a complex system provides novel insights however bedside application with clinical value remains wanting. Providing an integrative measure of an altered host response the patterns and character of heart rate fluctuations measured over intervals-in-time may be analysed with a panel of mathematical techniques that quantify overall fluctuation spectral composition scale-free variation and degree of irregularity or complexity. Using these techniques heart rate variability HRV has been documented to be both altered in the presence of systemic infection and correlated with its severity. In this review and analysis we evaluate the use of HRV monitoring to provide early diagnosis of infection document the prognostic implications of altered HRV in infection identify current limitations highlight future research challenges and