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báo cáo khoa học: "Different altered stage correlative expression of high abundance acute-phase proteins in sera of patients with epithelial ovarian carcinoma"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài:Different altered stage correlative expression of high abundance acute-phase proteins in sera of patients with epithelial ovarian carcinoma | BioMed Central Journal of Hematology Oncology Research Different altered stage correlative expression of high abundance acute-phase proteins in sera of patients with epithelial ovarian carcinoma Yeng Chen1 2 Boon-Kiong Lim3 4 and Onn H Hashim 1 4 Address Department of Molecular Medicine Faculty of Medicine University of Malaya 50603 Kuala Lumpur Malaysia institute for Research in Molecular Medicine INFORMM Universiti Sains Malaysia 11800 Minden Penang Malaysia 3Department of Obstetrics Gynecology Faculty of Medicine University of Malaya 50603 Kuala Lumpur Malaysia and 4University of Malaya Centre for Proteomics Research UMCPR University of Malaya 50603 Kuala Lumpur Malaysia Email Yeng Chen - chenyeng@hotmail.com Boon-Kiong Lim - limbk@ummc.edu.my Onn H Hashim - onnhashim@um.edu.my Corresponding author Open Access Published 27 August 2009 Received 22 June 2009 Journal of Hematology Oncology 2009 2 37 doi 10.1186 1756-8722-2-37 Accepted 27 August 2009 This article is available from http www.jhoonline.Org content 2 1 37 2009 Chen et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract__ Background The general enhanced expression of a1-antichymotrypsin ACT clusterin CLU a1-antitrypsin AAT haptoglobin P-chain HAP and leucine rich glycoprotein LRG in the sera of patients with epithelial ovarian carcinoma EOCa was recently reported. In the present study we compared the expression of the serum acute-phase proteins APPs in the patients according to their stages of cancer. Results Different altered stage correlative expression of the high abundance serum APPs was demonstrated in sera of the patients studied. While the expression of ACT HAP and AAT .