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Bio markers for patient stratification

Genetic factors and environmental factors - lifestyle, personal and family medical history - need to be considered for a complete picture of risk assessment. This is because each of these types of risk factors has advantages and limitations in informing risk. For example, family medical history can capture general risk information for genetic factors inherited from one’s parents, but can be incomplete, unknown, or recalled inaccurately. Indeed, family medical history can often be one-dimensional and is affected by family size. Furthermore, family medical history is a summation of both genetic and environment factors, making it sometimes difficult to tease those. | Brussels 10-11 ILJNE 2010 European Com -mission Health Rosea-rch Directorate Organisers FOR PATIENT STRATIFICATION 1 12 2 12 SUMMARY REPORT Stratification biomarkers in personalised medicine Workshop to clarify the scope for stratification biomarkers and to identify bottlenecks in the discovery and the use of such biomarkers. European Commission DG Research - Brussels 10-11 June 2010 3 .