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Báo cáo y học: " Plant polycistronic precursors containing non-homologous microRNAs target transcripts encoding functionally related proteins"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Plant polycistronic precursors containing non-homologous microRNAs target transcripts encoding functionally related proteins. | Open Access Researc h Plant polycistronic precursors containing non-homologous microRNAs target transcripts encoding functionally related proteins Francisco Merchant Adnane Boualem Martin Crespi and Florian Frugier Addresses Institut des Sciences du Végétal ISV Centre National de la Recherche Scientifique CNRS Avenue de la terrasse 91198 Gif sur Yvette cedex France. Current address Dto Microbiología y Parasitología Facultad de Farmacia Universidad de Sevilla C Profesor García Gonzalez 2 41012 Sevilla Spain. Unité de recherche en Génomique Végétale URGV Institut National de la Recherche Agronomique INRA Rue Gaston Crémieux 91057 Evry cedex France. Correspondence Adnane Boualem. Email boualem@evry.inra.fr. Martin Crespi. Email crespi@isv.cnrs-gif.fr Published 1 December 2009 Genome Biology 2009 10 R136 doi 10.1186 gb-2009-10-12-r136 The electronic version of this article is the complete one and can be found online at http genomebiology.com 2009 10 12 R136 Received 28 May 2009 Revised 14 September 2009 Accepted 1 December 2009 2009 Merchan et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.Org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background MicroRNAs miRNAs are endogenous single-stranded small RNAs that regulate the expression of specific mRNAs involved in diverse biological processes. In plants miRNAs are generally encoded as a single species in independent transcriptional units referred to as MIRNA genes in contrast to animal miRNAs which are frequently clustered. Results We performed a comparative genomic analysis in three model plants rice poplar and Arabidopsis and characterized miRNA clusters containing two to eight miRNA species. These clusters usually encode miRNAs of the same family and certain share a common evolutionary origin across monocot .