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Báo cáo hóa học: " The effects of diabetes and/or peripheral neuropathy in detecting short postural perturbations in mature adults"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: The effects of diabetes and/or peripheral neuropathy in detecting short postural perturbations in mature adults | Fulk et al. Journal of NeuroEngineering and Rehabilitation 2010 7 44 http www.jneuroengrehab.eom content 7 1 44 l dl JOURNAL OF NEUROENGINEERING NCR AND REHABILITATION RESEARCH Open Access The effects of diabetes and or peripheral neuropathy in detecting short postural perturbations in mature adults 1.2 245 23 6 7 George D Fulk 1 Charles J Robinson Sumona Mondal Christopher M Storey Anne M Hollister Abstract Background This study explored the effects of diabetes mellitus DM and peripheral neuropathy PN on the ability to detect near-threshold postural perturbations. Methods 83 subjects participated 32 with type II DM 25 with PN and 7 without PN 19 with PN without DM and 32 without DM or PN. Peak acceleration thresholds for detecting anterior platform translations of 1 mm 4 mm and 16 mm displacements were determined. A 2 DM X 2 PN factorial MANCOVA with weight as a covariate was calculated to compare acceleration detection thresholds among subjects who had DM or did not and who had PN or did not. Results There was a main effect for DM but not for PN. Post hoc analysis revealed that subjects with DM required higher accelerations to detect a 1 mm and 4 mm displacement. Conclusion Our findings suggest that PN may not be the only cause of impaired balance in people with DM. Clinicians should be aware that diabetes itself might negatively impact the postural control system. Background Complications associated with diabetes are linked to increased postural sway slowing of peripheral sensory and motor pathways abnormal neuromuscular response to postural disturbance increased whole body reaction time and abnormal gait patterns over irregular surfaces 1-3 . These complications may lead to impaired postural control and play a role in the increased risk of falling in this population 4 . Various authors have found that individuals with diabetes and peripheral neuropathy demonstrate impaired postural control in quiet standing compared to healthy control subjects. Boucher and .