tailieunhanh - Báo cáo hóa học: " Effects of Metal Ions on Conductivity and Structure of Single DNA Molecule in Different Environmental Conditions"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Effects of Metal Ions on Conductivity and Structure of Single DNA Molecule in Different Environmental Conditions | Nanoscale Res Lett 2010 5 1431-1436 DOI s11671-010-9657-3 NANO EXPRESS Effects of Metal Ions on Conductivity and Structure of Single DNA Molecule in Different Environmental Conditions Ruixin Dong Xunling Yan Ke Li Ge Ban Minghong Wang Shouxin Cui Bing Yang Received 23 March 2010 Accepted 19 May 2010 Published online 4 June 2010 The Author s 2010. This article is published with open access at Abstract We design a novel nano-gap electrode to measure the current of DNA molecule by which the current-voltage characteristics of individual native DNA Ag-DNA and Ni-DNA molecules are obtained respectively. The results show that the voltage gap of Ag- and Ni-DNA is higher than that of native DNA and the conductance is lower than native DNA in neutral environment. The structure transition from B- to Z-DNA is observed in the presence of high concentrations of nickel ions and Ag-DNA appears chaos state by STM image and U-V spectra characterization. But in alkaline environment the conductance of Ni-DNA rises and the voltage gap decreases with the increasing of nickel ion concentration denotes that the conductive ability of Ni-DNA is higher than that of native DNA. Keywords DNA Metal ions Nano-gap electrode Conductivity Structure Introduction With the development of high-speed processing technology more integrated silicon devices will be expected to reach a new level. Consequently some new materials worked in nano-scale are strongly desired. In this aspect DNA has received some attentions 1-3 . During the past few decades DNA has taken center stage in biophysical R. Dong X. Yan K. Li G. Ban M. Wang S. Cui B. Yang School of Physics Science and Information Technology Liaocheng University 252059 Liaocheng Shandong People s Republic of China e-mail dongruixin@ chemistry research. The elucidation of the molecule structure 50 years ago and the translating of genetic code revolutionized the field of biotechnology. Biologically the function of DNA is to