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SAFE USE OF CHEMICALS: A Practical Guide - Chapter 9

Phát triển công nghiệp và sử dụng các chất hóa học khác nhau liên quan chặt chẽ với hoạt động của con người. Rõ ràng, số lượng lớn người lao động có liên quan với số lượng lớn không kém của ngành công nghiệp trên khắp thế giới. Công nhân và công chúng nói chung đã được sử dụng, xử lý, và vận chuyển các chất hóa học trong những thập kỷ. Danh sách các chất hóa học công nghiệp là rất lớn và liên kết với những tác động nhiều đến sức khỏe con người. Hóa chất đã trở. | 9 Chemical Substances and Neurotoxicity 9.1 INTRODUCTION Industrial development and use of different chemical substances are closely related with human activities. Obviously large numbers of workers are associated with equally large numbers of industry around the world. Workers and the general public have been using handling and transporting many chemical substances over the decades. The list of industrial chemical substances is huge and linked with many implications to human health. Chemicals have become an indispensable part of human life sustaining activities and development preventing and controlling many diseases and increasing agricultural productivity. Despite their benefits chemicals may especially when misused cause adverse effects on human health. The nervous system has been shown to be particularly vulnerable to certain chemical exposures and there is increasing global concern about the potential health effects from exposure to neurotoxic chemicals. It has been well proved now that exposure to chemical substances causes adverse effects on the nervous system by inducing neurotoxicity. Prolonged exposure to chemical substances as is common in workplaces may lead to neurological disorders and damage the central nervous system CNS . In fact neurotoxicity disturbs the normal activity of the nervous system and eventually disrupts or even kills neurons the key cells that are responsible for the transmittance of signals in the brain and other parts of the nervous system. The symptoms of neurotoxicity may appear immediately after an exposure to toxic chemical substances or may be delayed. The poisoned worker can show several symptoms that include but are not limited to fatigue limb weakness numbness loss of memory and vision headache cognitive and behavioral problems such as confusion irritability behavioral changes degenerative diseases of the brain and encephalopathy peripheral nervous system problems paralysis tingling in the limbs paresthesia loss of .