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Báo cáo y học: "Assessing the origin of species in the genomic era"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Assessing the origin of species in the genomic era. | Minireview Assessing the origin of species in the genomic era Leonie C Moyle Addresses Center for Population Biology 2320 Storer Hall University of California Davis CA 95616 USA. E-mail lcmoyle@ucdavis.edu. Current address Department of Biology 1001 East Third Street Indiana University Bloomington IN 47405 USA. E-mail lmoyle@indiana.edu Published 31 March 2005 Genome Biology 2005 6 217 doi l0.ll86 gb-2005-6-4-2l7 The electronic version of this article is the complete one and can be found online at http genomebiology.com 2005 6 4 217 2005 BioMed Central Ltd Abstract Advances in genomics have rapidly accelerated research into the genetics of species differences reproductive isolating barriers and hybrid incompatibility. Recent genomic analyses in Drosophila species suggest that modified olfactory cues are involved in discrimination that is reinforced by natural selection. Ever since Darwin laid out overwhelming evidence for the mutability of species biologists have sought to explain the forces driving the genesis of new species and the genetic changes involved in speciation. Frequently this goal has been translated into the study of the genetic basis of species differences especially the genetic causes of inviability or sterility in hybrids between species. Despite creative early approaches to these problems 1 however classical genetic studies provided insufficient resolution for identifying the specific genomic regions and genes responsible for these traits. It is unsurprising then that the field of speciation genetics is being revolutionized by the rapidly expanding availability of genomic tools techniques and data especially in the model speciation systems such as Drosophila. The resulting contemporary studies of the genetics of speciation most frequently involve detailed linkage-mapping analyses of the quantitative trait loci QTLs underlying the isolating barriers and hybrid incompatibility between closely related species. The genomics of species divergence and .