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Báo cáo y học: " Level of dietary protein intake affects glucose turnover in endurance-trained men"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Level of dietary protein intake affects glucose turnover in endurance-trained men | Pasiakos et al. Journal of the International Society of Sports Nutrition 2011 8 20 http www.jissn.eom content 8 1 20 jissn journal of the international lociety of rporti nutrition SHORT REPORT Open Access Level of dietary protein intake affects glucose turnover in endurance-trained men Stefan M Pasiakos William F Martin Charu S Sharma Matthew A Pikosky Patricia C Gaine Douglas R Bolster Brian T Bennett and Nancy R Rodriguez Abstract Background To examine the effects of higher-protein diets on endogenous glucose metabolism in healthy physically active adults glucose turnover was assessed in five endurance-trained men age 21.3 0.3 y VO2peak 70.6 0.1 mL kg-1 min-1 who consumed dietary protein intakes spanning the current dietary reference intakes. Findings Using a randomized crossover design volunteers consumed 4 week eucaloric diets providing either a low 0.8 g kg-1 d-1 LP moderate 1.8 g kg-1 d-1 MP or high 3.6 g kg-1 d-1 HP level of dietary protein. Glucose turnover Ra glucose rate of appearance and Rd glucose rate of disappearance was assessed under fasted resting conditions using primed constant infusions of 6 6-2H2 glucose. Glucose Ra and Rd mg kg-1 min-1 were higher for MP 2.8 0.1 and 2.7 0.1 compared to HP 2.4 0.1 and 2.3 0.2 P 0.05 and LP 2.3 0.1 and 2.2 0.1 P 0.01 diets. Glucose levels mmol L were not different P 0.05 between LP 4.6 0.1 MP 4.8 0.1 and HP 4.7 0.1 diets. Conclusions Level of protein consumption influenced resting glucose turnover in endurance athletes in a state of energy balance with a higher rate of turnover noted for a protein intake of 1.8 g kg-1 d-1. Findings suggest that consumption of protein in excess of the recommended dietary allowance but within the current acceptable macronutrient distribution range may contribute to the regulation of blood glucose when carbohydrate intake is reduced by serving as a gluconeogenic substrate in endurance-trained men. Introduction Increasing dietary protein at the expense of carbohydrate in either Type