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Báo cáo y học: "Herpes simplex 1 encephalitis presenting as a brain haemorrhage with normal cerebrospinal fluid analysis: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Herpes simplex 1 encephalitis presenting as a brain haemorrhage with normal cerebrospinal fluid analysis: a case report | Journal of Medical Case Reports BioMed Central Open Access Case report Herpes simplex I encephalitis presenting as a brain haemorrhage with normal cerebrospinal fluid analysis a case report Effrossyni Gkrania-Klotsas 1 and Andrew ML Lever1 2 Address 1Addenbrooke s Hospital University of Cambridge Teaching Hospital NHS Trust Hills Road Cambridge CB2 2QQ UK and 2Department of Medicine University of Cambridge Hills Road Cambridge CB2 2QQ UK Email Effrossyni Gkrania-Klotsas - egkraniaklotsas@nhs.net Andrew ML Lever - amll1@mole.bio.cam.ac.uk Corresponding author Published 17 December 2008 Received 20 February 2008 Journal of Medical Case Reports 2008 2 387 doi l0.ll86 l752-l947-2-387 Accepted 17 December 2008 This article is available from http www.jmedicalcasereports.cOm content 2 l 387 2008 Gkrania-Klotsas and Lever licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Herpes simplex encephalitis is a potentially lethal infection that should be recognised as soon as possible. The combination of clinical history and examination brain computed tomography or magnetic resonance imaging and lumbar puncture has been used to establish a diagnosis. Case presentation We present a patient who had a suggestive history but a totally normal lumbar puncture and only evidence of intracerebral haemorrhage in the brain magnetic resonance imaging. Diagnosis was made by using the cerebrospinal fluid polymerase chain reaction for herpes simplex virus. Conclusion Herpes simplex encephalitis is being increasingly diagnosed with the availability of new diagnostic techniques. Herpes simplex encephalitis can present with the combination of haemorrhage and normal cerebrospinal fluid. Awareness of this common but if left untreated .