Đang chuẩn bị liên kết để tải về tài liệu:
Báo cáo y học: "Cytomegalovirus infection in critically ill patients: a systematic review"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Cytomegalovirus infection in critically ill patients: a systematic review. | Available online http ccforum.eom content 13 3 R68 Research Cytomegalovirus infection in critically ill patients a systematic review Ryosuke Osawa1 2 and Nina Singh1 2 Infectious Diseases Section VA Medical Center University Drive C Pittsburgh PA 15420 USA 2Division of Infectious Diseases Department of Medicine University of Pittsburgh 3601 Fifth Avenue Falk Medical Building Suite 3A Pittsburgh PA 15213 USA Corresponding author Nina Singh nis5@pitt.edu Received 28 Jan 2009 Revisions requested 5 Mar 2009 Revisions received 25 Mar 2009 Accepted 14 May 2009 Published 14 May 2009 Critical Care 2009 13 R68 doi 10.1186 cc7875 This article is online at http ccforum.com content 13 3 R68 2009 Osawa and Singh et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction The precise role of cytomegalovirus CMV infection in contributing to outcomes in critically ill immunocompetent patients has not been fully defined. Methods Studies in which critically ill immunocompetent adults were monitored for CMV infection in the intensive care unit ICU were reviewed. Results CMV infection occurs in 0 to 36 of critically ill patients mostly between 4 and 12 days after ICU admission. Potential risk factors for CMV infection include sepsis requirement of mechanical ventilation and transfusions. Prolonged mechanical ventilation 21 to 39 days vs. 13 to 24 days and duration of ICU stay 33 to 69 days vs. 22 to 48 days correlated significantly with a higher risk of CMV infection. Mortality rates in patients with CMV infection were higher in some but not all studies. Whether CMV produces febrile syndrome or end-organ disease directly in these patients is not known. Conclusions CMV infection frequently occurs in critically ill .